When printing Avery business cards, there is a template section often found in the software you are using. So answer a few questions for me please so I can guide you to the correct settings to adjust.
1. What is the operating system of the computer you are working on?
2. What program are you printing from (Word, Publisher, etc)?
3. What is the Avery card # on the packaging? It is usually in tiny print off to the side of the box the cards came in.
Here is a very interesting solution offered by AuntiEm I had never thought of before - "Avery Business Card Alignment Problem." It is not a very long forum thread but it offers a different take on the matter in case you have already made the proper changes within the software you are currently using.
If the above post doesn't help you, please answer my questions and I will be more than happy to help.